Ester-C® is the most bioavailable form of vitamin C ever developed. Metabolites in Ester-C® help the vitamin enter the cells more efficiently i.e. faster and in larger amounts. Better Absorbed Ester-C® is absorbed into the bloodstream twice as fast as ordinary vitamin C (ascorbic acid). Ester-C® calcium ascorbate contains a significant level of the natural C metabolite threonate, which is the key to enhancing blood and tissue concentrations of vitamin C. Better Retained Studies have shown that Ester-C® calcium ascorbate remains in the body twice as long as ordinary vitamin C. Studies also demonstrated that: Ester-C® promotes rapid absorption and delays the excretion of ascorbic acid.Ester-C® increases white blood cell ascorbate levels up to 4 times more than ascorbic acid, with as little as one third as much wasted.After 24 hours, retained Ester-C® blood concentration levels are 2 times greater than that of ascorbic acid.Ester-C® is effective in maintaining ascorbate levels. This is crucial to the delivery and metabolic utilization of ascorbate to targeted tissues. Third Generation Technology Ester-C®'s exclusive water-based manufacturing process uses no alcohol or any other harmful solvents. Better Tolerated When taking large amounts of vitamin C as ascorbic acid, many people experience flatulence, diarrhoea and discomfort. This is known as ‘acid rejection syndrome’ and occurs when acidic vitamin C enters the more alkaline environment of the lower digestive tract. Because Ester-C® is pH neutral, it does not cause these upsets and is gentle on the stomach.